NCT07259941

PET-CT in Lymphoma Among the Eldery

PET-CT Imaging Findings and Metabolic Parameters in Elderly Patients With Lymphoma

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 63 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: —

Summary

This study investigates PET-CT imaging patterns and metabolic parameters in elderly patients (≥60 years) diagnosed with lymphoma, aiming to enhance diagnostic accuracy and prognosis using 18F-FDG PET/CT scans.

Detailed description

This cross-sectional study involves both retrospective and prospective data collection from elderly lymphoma patients (aged 60 years or older) at the Nuclear Medicine Unit, South Egypt Cancer Institute. It evaluates the PET-CT imaging findings alongside metabolic parameters such as Standardized Uptake Value (SUV), Metabolic Tumor Volume (MTV), and Total Lesion Glycolysis (TLG). The study addresses diagnostic challenges in elderly patients due to atypical presentations and comorbidities and fills the gap of scarce local data in Egypt. Imaging analysis includes visual and semiquantitative assessment of lymphatic and extranodal lesions post-injection of 18F-FDG, assessing tumor metabolic activity to provide prognostic insights. Data analysis uses SPSS with relevant statistical tests to validate findings.

Conditions

• PET-CT
• Lymphoma
• Elderly
• Metabolic Parameters

Timeline

• Start date: 2026-01-01
• Primary completion: 2027-01-01
• Completion: 2027-02-01
• First posted: 2025-12-02
• Last updated: 2025-12-02