NCT07256717

BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation

Balanced Progressive Intensity Training (BPIT): A Five-Week Multi-Site Clinical Evaluation of Functional Movement, Mobility, and Neuromuscular Adaptation in Healthy Adults (18-65 Years)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 369 (estimated)
• Sponsor: MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years. All participants receive supervised BPIT sessions (3-5 per week) progressing through five intensity lines defined by anatomical landmarks and ground reaction force: Ground-Based (Low) Knee-Level (Low-Moderate) Standing (Moderate) Head-Level (Moderate-High) Plyometric (High-Impact) The study aims to quantify improvements in functional movement efficiency, joint mobility, postural control, strength adaptation, and heart-rate variability while monitoring safety and individual overload indicators.

Detailed description

Primary Outcome Measures Change in Functional Movement Screen (FMS) total score from baseline to Week 5 Change in Y-Balance Test reach distance (composite score) Timeframe: Baseline and Week 5 Secondary Outcome Measures Change in 1-RM or estimated strength (squat, deadlift, overhead press) Change in resting HRV (RMSSD) Change in joint range of motion (goniometry) and postural sway Incidence of training-related discomfort or minor injury Timeframe: Baseline, weekly, and Week 5 Arms/Intervention Experimental: BPIT 5-Line Training Group Intervention: Behavioral: Balanced Progressive Intensity Training (BPIT) 5-Line Method Description: 5-week supervised progressive training using the BPIT 5-Line framework (ground-based → plyometric) Eligibility Ages Eligible: 18 Years to 65 Years Sexes Eligible: All Accepts Healthy Volunteers: Yes Inclusion Criteria Healthy adults with regular exercise history Able to attend 3-5 training sessions/week Signed informed consent Exclusion Criteria Recent injury (\<3 months) Known cardiovascular, metabolic, or orthopaedic contraindications Pregnancy Study Locations 13 Locations in India 2 Locations in USA, (Details of the location is uploaded on mmsxauthority.com webiste) MMSx Authority , USA, GFFI Fitness Academy, New Delhi BodyGNTX USA BFS/AIHFT-approved facilities Countries of Recruitment India U.S. FDA-regulated? No / No / No Human Subjects Protection Review Board Status Approved (or Submit for review if not yet) Board Name: Institutional Ethics Committee - MMSx Authority / GFFI Approval Number: BPIT-MULTI-2025-001 (or pending) Data Monitoring Committee No

Conditions

• Physical Fitness

Interventions

Type	Name	Description
BEHAVIORAL	Balanced Progressive Intensity Training (BPIT) 5-Line Method	5-week supervised progressive training using the BPIT 5-Line framework developed by Dr. Neeraj Mehta.

Timeline

• Start date: 2025-10-10
• Primary completion: 2026-02-15
• Completion: 2026-02-25
• First posted: 2025-12-01
• Last updated: 2025-12-16

Locations

10 sites across 2 countries: United States, India