NCT07252687

The Effect of Gender-affirmative Measures on Breast Perception in Trans Men

The Effect of Gender-affirmative Measures on Breast Perception in Trans Men (TRANSBREAST) - a Prospective Cohort Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Medical University Innsbruck · Academic / Other
• Sex: Female
• Age: 16 Years
• Healthy volunteers: —

Summary

Breast dysphoria in transmasculine or genderdiverse individuals is a distinct psychological burden associated with depression, anxiety and suicidality. The aim is to systematically investigate the effect of GAHT (gender-affirming hormone therapy) and mastectomy on this form of dysphoria. The primary objective of this study is to analyse and investigate the psychological and physical effects of breast development on trans men or genderdiverse individuals. A secondary objective is to determine the extent to which the stress affects the well-being of trans men depending on the coping strategies used (binding vs. taping).

Conditions

• Transgender
• Gender Dysphoria in Adolescents and Adults

Interventions

Type	Name	Description
OTHER	quality of life questionnaire- iTransQoL, chest dysphoria measure	Before starting treatment, participants should complete the Chest Dysphoria Measure and iTransQoL questionnaires (=time point 0). The second time point for completing the questionnaires again is 3 months after starting hormone therapy. Subsequently, the questionnaires should be completed a third time after breast-affirming surgery. The final survey takes place two years after time point 0, or 6 months after the previous survey.

Timeline

• Start date: 2025-11-30
• Primary completion: 2030-11-01
• Completion: 2030-11-01
• First posted: 2025-11-28
• Last updated: 2026-03-06

Locations

1 site across 1 country: Austria