NCT07250256

Radiographic and Histomorphometric Evaluation of Xenograft as a Socket Preservation Material in Maxillary Posterior Teeth.

Radiographic and Histomorphometric Evaluation of Xenograft as a Socket Preservation Material in Maxillary Posterior Teeth: A Randomized-Controlled Clinical Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Suez Canal University · Academic / Other
• Sex: Male
• Age: 21 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Radiographic and Histomorphometric Evaluation of Xenograft as a Socket Preservation Material in Maxillary Posterior Teeth: A Randomized-Controlled Clinical Study

Detailed description

The process of natural healing starts with new bone formation taking place from initial islands of bone within the connective tissue occurring after a 4 to 8 weeks interval from extraction date. This is followed by the manifestation of a mature trabecular structure that can be noticed at 10 to 20 weeks after extraction accompanied with a reduction in osteoblast count. As a result of the extensive bone resorption post extraction, the prosthetically driven implant placement is compromised and in need of some ridge preservation techniques that have been widely studied to try and ensure less alveolar bone loss. The aim of this research is to study the S1-XB Xenograft containing hydrogel and to evaluate its effects on extraction socket healing in comparison to natural socket healing. This is an In-Vivo comparative randomized controlled study that will be conducted on patients of the outpatient clinic of Oral and Maxillofacial department Suez Canal University to evaluate the difference between using S1-XB bone graft as a socket preservation material and normal socket healing without adding any socket preservation materials.

Conditions

• Socket Preservation

Interventions

Type	Name	Description
DEVICE	S1-XB	Socket grafted with xenograft containing alginate hydrogel material
PROCEDURE	Control (Standard treatment)	Atraumatic extraction and sockets were allowed to undergo normal healing without any graft materials

Timeline

• Start date: 2022-08-01
• Primary completion: 2024-08-01
• Completion: 2024-12-01
• First posted: 2025-11-26
• Last updated: 2025-11-26

Locations

1 site across 1 country: Egypt