NCT07248410

A Split-Scalp Study Evaluating the Efficacy and Safety of Fractional Laser Therapy With and Without Exosomes in the Treatment of Androgenetic Alopecia

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Chang Gung Memorial Hospital · Academic / Other
• Sex: Male
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This trial aims to evaluate the efficacy, safety, and tolerability of fractional laser combined with topical exosome for hair regrowth in patients with androgenetic alopecia. This study is expected to recruit 30 participants. The experimental group will receive fractional laser treatment combined with human umbilical cord mesenchymal stem cell exosome solution; the control group will receive fractional laser treatment combined with a placebo. Participants will receive three fractional laser treatments and will be followed up for 6 months. At each follow-up visit, hair density, diameter, vellus hair to terminal hair ratio, and adverse reactions will be assessed using trichotomy; a global photographic assessment will be performed using standardized imaging equipment.

Conditions

• Androgenetic Alopecia

Interventions

Type	Name	Description
DEVICE	fraction laser	We will performed the fraction laser on the scalp of participants with energy of 30-40mJ every month for 3 times.

Timeline

• Start date: 2025-11-24
• Primary completion: 2027-09-30
• Completion: 2027-10-31
• First posted: 2025-11-25
• Last updated: 2025-11-25

Locations

1 site across 1 country: Taiwan