NCT07247994

Neurological Manifestations in Children Diagnosed With Inflammatory Bowel Disease

Neurological Manifestations in Children Diagnosed With Inflammatory Bowel Disease in Assiut University Child Hospital

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 44 (estimated)
• Sponsor: Bishoy Shehata Fahim · Academic / Other
• Sex: All
• Age: 1 Year – 18 Years
• Healthy volunteers: Not accepted

Summary

screen for neurologic and psychiatric disorders in children and adolescents with IBD.

Detailed description

Neurologic symptoms have a great importance in early diagnosis and treatment preventing major morbidity and later sequelae, especially if they precede GI symptoms The prevalence of neurologic manifestations of IBD varies between 0.2% and 36%. Their pathogenesis of neurologic manifestations in IBD consists of 6 mechanisms: 1.malabsorption and nutritional deficiency 2.metabolic agents 3.infections complicating immune suppression 4.side effects of medications or iatrogenic as a surgical complication 5.thromboembolism 6.immunological factors UC patients are similar to or higher than CD patients in the probability of neurologic symptoms. Neurologic manifestations and complications include: headache, dizziness, hypotonia, ADHD, tics, sensory complaints, seizures, neuropsychiatric disorders, peripherial neuropathy, meningitis, vestibular dysfunction, idiopathic IC hypertension, cerebral vasculitis, demyelinating disorders and migraine

Conditions

• IBD (Inflammatory Bowel Disease)

Timeline

• Start date: 2026-01-01
• Primary completion: 2027-01-01
• Completion: 2027-03-01
• First posted: 2025-11-25
• Last updated: 2025-11-25