NCT07247435

Role of CT in Tetralogy of Fallot Diagnosis

Role of Computed Tomography in Diagnosis of Syndromic and Non Syndromic Tetralogy of Fallot

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 37 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the role of MSCT in diagnosis and surgical planning in tetralogy of Fallot cases.

Detailed description

Role of Computed tomography (CT) : CT has become an indispensable imaging modality in the comprehensive evaluation and management of Tetralogy of Fallot (ToF). While echocardiography remains the initial diagnostic tool, CT offers unparalleled spatial resolution and the ability to generate high-quality, three-dimensional reconstructions of both intracardiac and extracardiac anatomy. This is particularly valuable for identifying associated anomalies such as major aortopulmonary collateral arteries (MAPCAs), anomalous coronary artery origins, and variations in pulmonary artery branching patterns that can significantly influence surgical decision-making. Preoperatively, CT enables precise assessment of the severity and extent of right ventricular outflow tract obstruction, ventricular septal defect morphology, and the relationship of the overriding aorta to the interventricular septum. Overall, CT complements other imaging modalities by providing a fast, accurate, and comprehensive anatomical roadmap that guides surgical planning, informs long-term follow-up, and aids in the early detection of complications. Its role is particularly pronounced in complex and syndromic cases of ToF, where anatomical variations are more common and precise preoperative mapping is critical for successful outcomes.

Conditions

• Cardiac CT TOF

Interventions

Type	Name	Description
DEVICE	Computed tomography	Radiological device

Timeline

• Start date: 2025-11-15
• Primary completion: 2028-09-15
• Completion: 2028-09-15
• First posted: 2025-11-25
• Last updated: 2025-11-25