NCT07246161

Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women

Detection of Orally Delivered Probiotic Strains in the Vaginal Microbiome of Healthy Female Adults

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 72 (estimated)
• Sponsor: Lallemand Health Solutions · Industry
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of the present study is to obtain more information on the transit of orally ingested probiotics to the vagina.

Detailed description

Probiotics have emerged as novel supplements to support women's health, demonstrating benefits in maintain vaginal health and promoting recovery from dysbiosis. This includes various oral and vaginal probiotics shown to alleviate symptoms and enhance the reversal of vaginal dysbiosis. Oral delivered probiotic strains suggest their ability to migrate and colonize the vagina to support vaginal health but is not well understood. Therefore, this study will aim to provide additional information on their transit to the vagina.

Conditions

• Focus is on Healthy Subjects

Interventions

Type	Name	Description
OTHER	Probiotic Formula 1	Includes 2 different probiotic strains differing from other intervention groups.
OTHER	Probiotic Formula 2	Includes 2 different probiotic strains differing from other intervention groups.
OTHER	Probiotic Formula 3	Includes 2 different probiotic strains differing from other intervention groups.

Timeline

• Start date: 2025-10-20
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2025-11-24
• Last updated: 2025-11-26

Locations

1 site across 1 country: Canada