NCT07245979

Supplementation With Sirtuin Activators in Women With Increased Body Weight

Assessment of the Effect of Sirtuin Activator Supplementation on Cellular, Metabolic and Anthropometric Parameters in Women

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Poznan University of Life Sciences · Academic / Other
• Sex: Female
• Age: 40 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are: Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing? Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status. Participants will: Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.

Conditions

• Obesity & Overweight

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Sirtuin activators	Sirtuin acitivators supplementation for 6 months
DIETARY_SUPPLEMENT	Placebo	Placebo supplementation for 6 months

Timeline

• Start date: 2025-10-08
• Primary completion: 2026-11-30
• Completion: 2027-03-01
• First posted: 2025-11-24
• Last updated: 2026-02-19

Locations

1 site across 1 country: Poland