NCT07244536

Effects of Physical Exercise and Cognitive Training on Quality of Life in Elderly Adults

Health-related Quality of Life in Elderly Adults Following Physical Exercise and Cognitive Training: a Randomized-controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 156 (estimated)
• Sponsor: University Hospital of Ferrara · Academic / Other
• Sex: All
• Age: 70 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to investigate the effectiveness of three different types of intervention, based on physical exercise and/or cognitive stimulation or training, on quality of life, cognition and mobility, on a population of older adults, who are most at risk of functional and cognitive decline

Conditions

• Elderly (People Aged 65 or More)

Interventions

Type	Name	Description
BEHAVIORAL	EXERCISE TRAINING WITH OR WITHOUT MEDICATION	The program includes 75-minute training sessions twice a week, for a total of 24 training sessions over 12 weeks. Each training session will be divided into a warm-up, training phase and cool-down, and will include aerobic exercises, resistance training, balance exercises, mobility exercises and stretching.
BEHAVIORAL	EXERCISE TRAINING WITH OR WITHOUT MEDICATION	In addition to the exercise program, Participants will be given a series of cognitive exercises aimed at improving prospective memory through the performance of certain oral tasks, administered by a member of the research team. All cognitive exercises will be adapted to the cognitive abilities of the participants.
BEHAVIORAL	EXERCISE TRAINING WITH OR WITHOUT MEDICATION	In addition to the exercise training, people will receive a short video lasting less than 10 minutes on their smartphone or tablet before the exercise session (or at home). At the end of the video, they will be asked to complete a 10-question questionnaire (also delivered via smartphone or tablet) with True or False answer options.

Timeline

• Start date: 2025-11-15
• Primary completion: 2027-10-31
• Completion: 2028-10-31
• First posted: 2025-11-24
• Last updated: 2025-12-12

Locations

1 site across 1 country: Italy