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Trials / Recruiting

RecruitingNCT07242781

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Drug Levels of AR-LDD (BMS-986365) in Healthy Adult Male Participants

A Phase 1, Open-label, 2-part, Fixed-sequence, Crossover Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Pharmacokinetics of AR-LDD (BMS-986365) in Healthy Adult Male Participants

Status
Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
42 (estimated)
Sponsor
Celgene · Industry
Sex
Male
Age
18 Years – 60 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to evaluate the effect of Itraconazole and Rifampin on the drug levels of AR-LDD (BMS-986365) in healthy adult male participants.

Conditions

Interventions

TypeNameDescription
DRUGBMS-986365Specified dose on specified days
DRUGItraconazoleSpecified dose on specified days
DRUGRifampinSpecified dose on specified days

Timeline

Start date
2025-12-15
Primary completion
2026-06-14
Completion
2026-06-14
First posted
2025-11-21
Last updated
2025-12-24

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT07242781. Inclusion in this directory is not an endorsement.

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Drug Levels of AR-LDD (BMS-986365) in Healthy Adult M (NCT07242781) · Clinical Trials Directory