Trials / Not Yet Recruiting
Not Yet RecruitingNCT07242261
Non-invasive Characterisation of Oral Carcinomas in Patients With Fanconi Anaemia
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 115 (estimated)
- Sponsor
- Institut Jean-Godinot · Academic / Other
- Sex
- All
- Age
- 15 Years
- Healthy volunteers
- Not accepted
Summary
Patients with Fanconi anaemia have an increased risk of developing squamous cell carcinoma of the head and neck. In addition, their genetic vulnerability limits the use of genotoxic treatments such as radiotherapy and chemotherapy, due to increased exposure to severe toxicities. Less invasive diagnostic techniques, such as brush biopsies, which rely on cytological and ploidy analysis, offer the possibility of more systematic, comprehensive and less painful oral mapping, thereby facilitating earlier diagnosis.
Detailed description
The aim of the study is to investigate the capabilities of oral brushing for the characterisation of oral lesions in patients with Fanconi anaemia.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Oral brushing | oral brushing of all oral lesions |
Timeline
- Start date
- 2026-04-01
- Primary completion
- 2030-04-01
- Completion
- 2030-10-01
- First posted
- 2025-11-21
- Last updated
- 2025-11-21
Source: ClinicalTrials.gov record NCT07242261. Inclusion in this directory is not an endorsement.