NCT07237685

Evaluating Atherosclerotic Disease Progression in Patients With Diabetes Mellitus

Evaluating Atherosclerotic Disease Progression in High-Risk Patients With Diabetes Mellitus

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

People with type 2 diabetes have a much higher risk of heart disease. One common problem is when the blood vessels that supply the heart become narrowed or blocked by fatty deposits, called plaque. This makes it harder for blood to reach the heart and can lead to serious problems such as chest pain, heart attacks, or even death. This study will follow people with type 2 diabetes who have already had a special heart scan called a coronary CT angiography. This scan takes detailed pictures of the heart's blood vessels. The goal is to understand how heart disease changes over time in people with type 2 diabetes, by looking at repeat scans and other health information. By learning more about how plaque builds up or gets worse, researchers hope to find better ways to identify which patients are most at risk for future heart problems.

Conditions

• Type 2 Diabetes
• Coronary Artery Disease (CAD)
• Atherosclerosis Cardiovascular Disease

Timeline

• Start date: 2025-06-06
• Primary completion: 2026-10-01
• Completion: 2036-10-01
• First posted: 2025-11-20
• Last updated: 2025-11-20

Locations

2 sites across 1 country: Netherlands