NCT07236775

Treatment Outcome of Clear Aligner and Traditional Fixed Appliances in Four Premolar Extraction Cases

Evaluation of the Apical Root Resorption in Young Adults Caused by Orthodontic Treatment of Class I Severe Crowding Cases Using Clear Aligners Versus Traditional Fixed Appliances: A Randomized Controlled Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Damascus University · Academic / Other
• Sex: All
• Age: 18 Years – 25 Years
• Healthy volunteers: Not accepted

Summary

Patients with severe crowding requiring the extraction of four premolars will be enrolled in this study. The degree of apical root resorption associated with using the clear aligner technique compared with vestibular fixed appliances in the treatment of severe crowding malocclusion cases requiring the extraction of first premolars will be evaluated using cone beam computed tomography (CBCT) volumes. There are two groups: First group (Experimental): the patients in this group will be treated using clear aligners. Second group (Control): the patients in this group will be treated using fixed appliances.

Detailed description

With the increasing number of young adults requesting esthetic orthodontic treatment, clear aligners have continued to gain widespread use, driven by greater consideration of esthetic aspects and oral health-related quality of life compared to traditional fixed orthodontic appliances. Recently, clear aligners have been used in more complex malocclusion cases that require premolar extraction. Teeth root resorption occurs due to physiological or pathological causes that lead to loss of tooth structure. Apical root resorption (ARR) is a common side effect of orthodontic treatment that requires careful investigation of its location and frequency.

Conditions

• Malocclusion, Class I/II
• Crowding, Tooth

Interventions

Type	Name	Description
DEVICE	Clear Aligners	In-house 3D-fabricated clear aligners will be used.
DEVICE	Traditional fixed appliances	The ordinary metallic braces will be used in a conventional manner.

Timeline

• Start date: 2019-11-10
• Primary completion: 2021-02-15
• Completion: 2022-02-23
• First posted: 2025-11-19
• Last updated: 2025-11-19

Locations

1 site across 1 country: Syria