NCT07233083

External Oblique Intercostal Plane Block for Liver Transplantation Recipient

External Oblique Intercostal Plane Block for Postoperative Analgesia in Liver Transplantation

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Istinye University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Postoperative pain management is one of the key factors in improving rehabilitation and accelerating recovery. The external oblique intercostal plane block can be used to provide abdominal wall analgesia for effective pain control in abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of the external oblique intercostal plane block in liver transplant recipients. The investigators will compare a group receiving the external oblique intercostal plane block with a control group to determine whether this block provides effective postoperative analgesia in liver transplant recipients.

Detailed description

Patients scheduled for liver transplantation will be separated into 2 groups: External Oblique Intercostal Plane Block Group and Control Group. Patients in the External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block at the end of the surgery and after skin closure and will receive patient controlled analgesia with morphine for postoperative analgesia. Patients in the Control Group will not receive any block procedure and will receive patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 48 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting, and Quality of Recovery-15 scores will be recorded.

Conditions

• Liver Transplantation
• Recipients of Liver Transplant
• Postoperative Pain

Interventions

Type	Name	Description
OTHER	External Oblique Intercostal Plane Block	External oblique intercostal plane block will be administered at the end of the surgery and after skin closure
OTHER	Sham Procedure	Sham Block (Ultrasound probe placement without needle insertion or injection)

Timeline

• Start date: 2025-12-22
• Primary completion: 2026-05-01
• Completion: 2026-06-01
• First posted: 2025-11-18
• Last updated: 2026-01-08

Locations

1 site across 1 country: Turkey (Türkiye)