NCT07231783

The Effect of Urolithin A (Mitopure®) Supplementation on Muscle Strength in Healthy Middle-Aged Adults

A Confirmatory, Randomised, Double-Blind, Placebo-Controlled, Parallel Study to Assess the Effects of a Dietary Supplement Containing Urolithin A (Mitopure®) on Muscle Strength and Performance in Healthy Middle-Aged Adults

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Amazentis SA · Industry
• Sex: All
• Age: 40 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This is a randomised, double-blind, placebo-controlled, parallel study to assess the effects of Urolithin A (Mitopure®) supplementation on muscle strength and performance in healthy middle-aged adults. Participants will be randomized to consume Mitopure® (500 mg), Mitopure® (1000 mg), or placebo once daily for 6 months.

Conditions

• Healthy Aging
• Muscle Function

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Placebo	Placebo softgels
DIETARY_SUPPLEMENT	Mitopure® 500mg	Softgels providing 500 mg of Mitopure®
DIETARY_SUPPLEMENT	Mitopure® 1000mg	Softgels providing 1000 mg of Mitopure®

Timeline

• Start date: 2025-12-10
• Primary completion: 2027-10-31
• Completion: 2027-10-31
• First posted: 2025-11-17
• Last updated: 2026-03-31

Locations

1 site across 1 country: Ireland