NCT07231003

The Effect of Glucomannan Powder on Improving Gut Microbiota.

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Taipei Medical University · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The object of this study is evaluating the effects of the Glucommanan on the healthy human subjects who are. In this trial, at most 30 healthy subjects whose ages are 20\~65 years old (15 for placebo and 15 for intervention)will be included. The total experiment will be 9 weeks and the intervention period will be 6 weeks, within which, at week 0, 6, and 7, total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), aspartate aminotransferase (AST, also known as GOT), alanine aminotransferase (ALT, also known as GPT), blood urea nitrogen (BUN), serum creatinine (Cr), fasting blood glucose (Glucose, AC) and adiponectin would be measured. Feces samples and anthropometric data will also be acquired. The results will be analyzed according to the methods published by the Ministry of Health and Welfare of Taiwan Food and Drug Administration.

Conditions

• Dysbiosis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Glucomannan	2 packs of glucomannan, 2 grams per pack
DIETARY_SUPPLEMENT	Placebo	2 packs of corn starch, 2 grams per pack

Timeline

• Start date: 2025-08-28
• Primary completion: 2026-08-31
• Completion: 2026-12-31
• First posted: 2025-11-17
• Last updated: 2025-11-17

Locations

1 site across 1 country: Taiwan