Trials / Completed
CompletedNCT07230522
Effectiveness of Hyaluronic Acid (hyaDENT BG® Gel) Compared With Enamel Matrix Proteins (Emdogain®) in the Treatment of Angular Bone Defects in Combination With a Xenograft (Bio-Oss Collagen®)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 17 (actual)
- Sponsor
- Medical University of Sofia · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this clinical trial is to learn whether hyaluronic acid (HyaDent® BG) provides similar benefits to Emdogain® when both are used with Bio-Oss® Collagen during periodontal surgery in adults with periodontal (intrabony) defects. The main questions it aims to answer are: Does the treatment reduce probing pocket depth? Does the treatment increase clinical attachment level? Does the treatment increase radiographic bone fill? Does the treatment change the gingival margin position? Researchers will compare Bio-Oss Collagen + HyaDent BG with Bio-Oss Collagen + Emdogain to see whether HyaDent BG achieves similar improvements in clinical and radiographic outcomes as Emdogain. Participants will: Undergo periodontal surgery to treat the vertical bone defect(s), with either Bio-Oss Collagen + HyaDent BG or Bio-Oss Collagen + Emdogain. Attend follow-up visits for periodontal measurements and radiographs.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Bio-Oss Collagen + HyaDent BG | Application of Bio-Oss® Collagen combined with HyaDent® BG (cross-linked hyaluronic acid gel) during periodontal surgery for intrabony defects. Standard regenerative protocols are followed. |
| BIOLOGICAL | Bio-Oss Collagen + Emdogain | Application of Bio-Oss® Collagen combined with Emdogain during periodontal surgery for intrabony defects. Standard regenerative protocols are followed. |
Timeline
- Start date
- 2024-03-12
- Primary completion
- 2024-07-31
- Completion
- 2025-01-10
- First posted
- 2025-11-17
- Last updated
- 2025-11-17
Locations
1 site across 1 country: Bulgaria
Source: ClinicalTrials.gov record NCT07230522. Inclusion in this directory is not an endorsement.