NCT07228234

Evaluating Mammography Communication Approaches

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,900 (estimated)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: Female
• Age: 39 Years – 49 Years
• Healthy volunteers: Accepted

Summary

This is a randomized online experiment testing different methods for communicating about the benefits and harms of breast cancer screening. Participants will be randomly assigned to experimental conditions which vary whether screening outcomes are referred to as "benefits and harms" vs. "outcomes that can happen with screening", and vary the presence or absence of information about improvements in breast cancer survivability. In a control condition, participants receive basic information about what mammography is (which is also information received in all other conditions). Primary outcomes include skepticism toward the information presented, and screening intentions.

Detailed description

This is a randomized online experiment testing different methods for communicating about the benefits and harms of breast cancer screening. Participants will be randomly assigned to 1 of 5 experimental conditions, in a 2 x 2 + 1 factorial design, which vary (1) whether screening outcomes are referred to as "benefits and harms" vs. "outcomes that can happen with screening", and (2) the presence or absence of information about improvements in breast cancer treatment and survivability. In a 5th arm, a control condition, participants receive basic information about what mammography is (which is also information received in all other conditions). Primary outcomes include skepticism toward the information presented, and screening intentions.

Conditions

• The Focus of This Study is to Identify How Different Approaches to Mammography Communication Affect Skepticism Toward Mammography Evidence

Interventions

Type	Name	Description
OTHER	Harm/benefit language vs. outcomes that can happen	Information about mortality benefit, false positives and overdiagnosis are referred to throughout the communication as either "harms" and "benefits" or "outcomes that can happen".
OTHER	Breast cancer survivability information	Information about improvements over time in the survivability of breast cancer is provided vs. not
OTHER	No intervention	This is the control condition in which only basic information about mammography screening.

Timeline

• Start date: 2025-11-06
• Primary completion: 2025-11-12
• Completion: 2027-11-30
• First posted: 2025-11-14
• Last updated: 2026-04-01

Locations

1 site across 1 country: United States