NCT07228104

Use of Steroid Injections to Prevent the Recurrence of Tracheal Stenosis in Idiopathic Subglottic Stenosis

Adjuvant STeRoid Outcomes in Idiopathic Subglottic Stenosis

• Status: Not Yet Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 226 (estimated)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study will examine the ability of steroid injections into the site of stenosis following surgical dilation to delay the need for repeated surgical dilations.

Conditions

• Idiopathic Subglottic Stenosis

Interventions

Type	Name	Description
DRUG	Triamcinolone 0.1%	Intralesional Triamcinolone injection 3x at one, two, and three months following surgical dilation
DRUG	Placebo	Intralesional Placebo injection 3x at one, two, and three months following surgical dilation

Timeline

• Start date: 2026-05-01
• Primary completion: 2031-01-01
• Completion: 2032-01-01
• First posted: 2025-11-14
• Last updated: 2026-03-16

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study