NCT07227142

IceBath: NOICE vs Nothing

NOICE: A Prospective, Randomized, Crossover Study (NOICE vs. Nothing)

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Accepted

Summary

This prospective, randomized, 2-period crossover study seeks to evaluate the effect of the non-visual immersive technology-based audio biofeedback intervention, delivered through devices such as NOICE device or Quest 3, on cold pain threshold within participants.

Detailed description

This study addresses the research gap in understanding how non-visual immersive technology-based audio biofeedback intervention impacts pain perception in clinical settings. It is important to explore this because non-visual immersive technology-based audio biofeedback intervention may serve as a non-pharmaceutical, non-visual immersive technology-based audio biofeedback alternative to traditional visual-based distraction methods like virtual reality. The investigators hypothesize that participants using the non-visual immersive technology-based audio biofeedback device will report an increased pain threshold compared to not using the device. This knowledge could improve information on the perception of pain for participant who prefer not to use Virtual Reality (VR) headsets.

Conditions

• Pain

Interventions

Type	Name	Description
BEHAVIORAL	Non-visual immersive technology-based audio biofeedback intervention	Participants receive real-time auditory feedback during cold pain endurance tasks.
BEHAVIORAL	Control (No non-visual immersive technology-based audio biofeedback)	Participants complete the same cold pain endurance tasks without any non-visual immersive technology-based auditory feedback.

Timeline

• Start date: 2026-04-01
• Primary completion: 2027-03-31
• Completion: 2027-03-31
• First posted: 2025-11-12
• Last updated: 2025-12-18

Locations

1 site across 1 country: United States