NCT07226596

Non-Abstinence Outcomes in Methamphetamine Use Disorder

Advancing Non-Abstinence Outcomes in the Treatment of Methamphetamine Use Disorder

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: William Stoops · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Reduced drug use is a clinically meaningful target for treatment development, but few studies have evaluated the positive impacts produced by this behavioral change, preventing adoption of this endpoint in clinical trials. The proposed research will fill that critical knowledge gap by demonstrating the biopsychosocial benefits of reduced methamphetamine use. These data will be used to change current accepted methamphetamine treatment endpoints and accelerate identification of therapies for methamphetamine use disorder.

Conditions

• Methamphetamine Use Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Contingency Management	Subjects will receive payments for providing methamphetamine negative urine samples.

Timeline

• Start date: 2026-01-14
• Primary completion: 2031-01-04
• Completion: 2031-01-04
• First posted: 2025-11-10
• Last updated: 2026-01-23

Locations

1 site across 1 country: United States