NCT07225309

A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

Trial of Meaning Centered Psychotherapy for Mexican Patients With Advanced Cancer

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT). Investigators also want to learn what participants and providers think about the therapy, including how the therapy is designed, outside factors, available resources, and how the people involved affect how well MCP-L works.

Conditions

• Breast Cancer
• Prostate Cancer
• Colorectal Cancer
• Thyroid Cancer
• Breast Cancer Stage III
• Breast Cancer Stage IV
• Prostate Cancer Stage III
• Prostate Cancer Stage IV
• Colorectal Cancer Stage III
• Colorectal Cancer Stage IV
• Thyroid Cancer Stage III
• Thyroid Cancer Stage IV

Interventions

Type	Name	Description
BEHAVIORAL	Meaning-Centered Psychotherapy for Latinos /MCP-L	MCP-L is a structured 7-session manualized intervention culturally adapted into Spanish for Latino participants diagnosed with advanced cancer, which utilizes a mixture of didactics, discussion and experiential exercises that focus on particular themes related to meaning and advanced cancer. It is 60-minute individual sessions delivered every week or intermittently (depending on participant preference) for up to approximately 3 months (in this time period) in the event of medical illness.

Timeline

• Start date: 2026-06-01
• Primary completion: 2029-04-13
• Completion: 2029-04-13
• First posted: 2025-11-06
• Last updated: 2026-04-14

Locations

2 sites across 2 countries: United States, Mexico