Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07222137

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Baricitinib to Delay Stage 3 Type 1 Diabetes in At-risk Participants Aged ≥1 to <36 Years

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
150 (estimated)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
1 Year – 35 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to find out if baricitinib can delay the onset of clinical type 1 diabetes (T1D) in people who are at high risk to develop T1D. Participation in the study will last up to approximately 5 years.

Conditions

Interventions

TypeNameDescription
DRUGBaricitinibAdministered orally
DRUGPlaceboAdministered orally

Timeline

Start date
2026-01-12
Primary completion
2031-07-01
Completion
2031-07-01
First posted
2025-10-29
Last updated
2026-04-17

Locations

107 sites across 18 countries: United States, Australia, Belgium, Brazil, Canada, Finland, France, Germany, Israel, Italy, Japan, Netherlands, Norway, Poland, Portugal, Spain, Sweden, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT07222137. Inclusion in this directory is not an endorsement.