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Trials / Recruiting

RecruitingNCT07221617

Oral Methadone in Cardiac Surgery

Oral Methadone In Cardiac Surgery

Status
Recruiting
Phase
Phase 4
Study type
Interventional
Enrollment
100 (estimated)
Sponsor
Mayo Clinic · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.

Conditions

Interventions

TypeNameDescription
DRUGMethadone, oralPatients will receive 0.4mg/kg PO methadone immediately prior to transport to the operating room
DRUGMethadone, intravenouslyPatients will receive 0.3mg/kg methadone intravenously after induction of general anesthesia

Timeline

Start date
2026-01-13
Primary completion
2026-06-30
Completion
2026-08-01
First posted
2025-10-28
Last updated
2026-01-14

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT07221617. Inclusion in this directory is not an endorsement.