Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07220915

Supporting Weak Immune System During Autoimmune Therapy: Testing Panzyga to Prevent Infections

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Panzyga for Prevention of Major Infection in Patients With Hypogammaglobulinemia and Autoimmune or Rheumatic Conditions Receiving Treatment With B-cell Depletion Therapy ("PROTECT")

Status
Not Yet Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
360 (estimated)
Sponsor
Octapharma · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Panzyga for Prevention of Major Infection in Patients with Hypogammaglobulinemia and Autoimmune or Rheumatic Conditions Receiving Treatment with B-cell Depletion Therapy

Conditions

Interventions

TypeNameDescription
DRUGPanzyga, 10% Intravenous SolutionPanzyga is a 10% Ig formulation for intravenous (IV) administration
OTHERPlacebo4 mL/kg 0.9% w/v sodium chloride solution per single IV infusion

Timeline

Start date
2025-12-01
Primary completion
2029-12-01
Completion
2029-12-01
First posted
2025-10-24
Last updated
2025-10-24

Regulatory

Source: ClinicalTrials.gov record NCT07220915. Inclusion in this directory is not an endorsement.