Trials / Recruiting
RecruitingNCT07220005
Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- Sponsor
- Duke University · Academic / Other
- Sex
- All
- Age
- 21 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this research study is to optimize the parameter of Low-Intensity Focused Ultrasound Stimulation (LIFUS) that is most effective in changing cortical excitability and motor learning skills in patients who suffered a stroke. The researchers hope to answer two questions. * with increasing power, would LIFUS be more effective? * with the same power, what LIFUS timing is the best For Aim 1, the study will compare 8, 4 W/cm\^2 to a zero(sham) stimulation to see if higher power is the better. For Aim 2, the study will compare 500 vs 1000 vs 2000 Hz "timing" to see which one is better.
Conditions
- Stroke
- Arm Weakness as a Consequence of Stroke
- Upper Extremity Hemiparesis
- Upper Extremity Impairments
- Upper Extremity Weakness
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Low intensity focused ultrasound stimulation | A low-intensity focused ultrasound stimulation |
Timeline
- Start date
- 2025-12-10
- Primary completion
- 2026-05-01
- Completion
- 2026-06-30
- First posted
- 2025-10-23
- Last updated
- 2025-12-23
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT07220005. Inclusion in this directory is not an endorsement.