NCT07219498

Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: University of Minnesota · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacillus casei probiotic strain reduces symptoms of delayed onset muscle soreness (DOMS) based on perceived muscle soreness, pressure pain threshold, and power output following exercise induced muscle damage (EIMD).

Conditions

• Exercise Induced Muscle Damage
• Delayed Onset Muscle Soreness (DOMS)

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lactobacillus casei	Probiohealth is the manufacturer of this strain and they use a stringent quality control program that utilizes a multi point product variability check system.
OTHER	Placebo Capsule(s)	The brand name of placebo capsules that will be used in this study is Magic Bullet Placebo Capsules. This placebo is manufactured by Progressive Placebo as stated on the product label.

Timeline

• Start date: 2026-02-05
• Primary completion: 2026-04-30
• Completion: 2026-04-30
• First posted: 2025-10-22
• Last updated: 2026-02-12

Locations

1 site across 1 country: United States