NCT07215338

Effects of Palmar Cooling on the Human Immune System

Understanding and Mitigating Delayed Onset Muscle Soreness (DOMS)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This is a research study on human exercise that will investigate the immune system response post-exercise and how it relates to Delayed Onset Muscle Soreness (DOMS), and possible causes for DOMS. Blood draws (10mL) will be obtained at 5 timepoints: Baseline before intervention, day of exercise immediately following exercise, and post-exercise days 1, 2 and 4. Point of care lactate levels obtained before and after exercise. Subjective pain scores recorded daily starting immediately after after exercise.

Conditions

• Human Immune Response

Interventions

Type	Name	Description
OTHER	Muscle Temperature Control	The intervention will be placing the palms of the hands on a water perfused pad.

Timeline

• Start date: 2024-06-28
• Primary completion: 2024-09-27
• Completion: 2024-09-27
• First posted: 2025-10-10
• Last updated: 2025-11-04

Locations

1 site across 1 country: United States