NCT07214155

Effects of Various Cannabis Strains on Perceptual, Subjective and Objective Use Outcomes

• Status: Not Yet Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 21 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study will evaluate the subjective and behavioral effects of cannabis products labeled as indica, sativa, or generic.

Detailed description

This clinical laboratory study will be double-blind, placebo-controlled and will utilize a within-subjects experimental design. Participants will complete 6 outpatient drug administration sessions that will consist of self-administration of smoked cannabis (0, or 25mg THC) labeled as indica, sativa, or generically-labelled. Primary outcomes include performance on cognitive and psychomotor assessments, subjective drug effects, and simulated driving performance. Smoking topography will also be characterized.

Conditions

• Cannabis Intoxication

Interventions

Type	Name	Description
DRUG	Cannabis	Cannabis will be administered via smoked inhalation.
OTHER	0 mg THC (placebo)	0 mg THC (placebo)

Timeline

• Start date: 2026-05-15
• Primary completion: 2029-06-01
• Completion: 2029-09-01
• First posted: 2025-10-09
• Last updated: 2026-04-17

Regulatory

• FDA-regulated drug study