NCT07213921

Dermabrasion in Mohs: Split-Scar Trial

Intraoperative Dermabrasion in Mohs Surgery: A Randomized Split-Scar Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: University of Wisconsin, Madison · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine the potential influence of intraoperative dermabrasion on scars following Mohs Micrographic Surgery (MMS). Researchers are trying to determine if dermabrasion, a method to gently remove the top layer of your skin, is a good or bad tool to improve scar appearance after healing. The use of dermabrasion technique in this study is considered investigational. 50 participants will be enrolled and on study for up to 6 months.

Detailed description

Primary Objective: Scar assessment at 3 months postoperatively by utilizing observer component of Patient and Observer Scar Assessment Scale (POSAS) Secondary Objectives: * Patient portion of POSAS * Overall patient opinion of scar appearance * Complication rate

Conditions

• Wound Heal

Interventions

Type	Name	Description
PROCEDURE	Dermabrasion	First, both sides of the wound will be sutured together with a subcutaneous (bottom) layer of stitches. Next, a predetermined, concealed randomization number will be obtained which will specify which side, A or B, will be treated with dermabrasion. An electrocautery scratch pad will be used along the wound edge of the intervention side until pin-point bleeding is achieved. This will add no additional time to the standard of care surgery time. The wound will then be closed with an epidermal (top) layer of stitches, as is the standard of care.

Timeline

• Start date: 2025-10-23
• Primary completion: 2026-09-01
• Completion: 2026-09-01
• First posted: 2025-10-09
• Last updated: 2025-10-31

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study