NCT07213362

Study on the Effect of Online Cognitive Training Doses on Cognitive Function in Individuals With Mild Cognitive Decline

Study on the Effect of Different Doses of Computerized Cognitive Training on Cognitive Function in Patients With Mild Cognitive Impairment: An Open-Label, Randomized, Controlled Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 234 (estimated)
• Sponsor: Peking University · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

The primary questions that this clinical trial aims to answer are: To compare the differences in the efficacy of different doses of Computerized Cognitive Training (CCT) in improving cognitive function among patients with Mild Cognitive Impairment (MCI), and to explore the potential optimal intervention dose. To analyze the interaction between individual characteristics and the intervention dose of CCT. To compare the improvement in functional activity ability of MCI patients among different CCT intervention dose groups. To compare the symptoms of depression and anxiety among different CCT intervention dose groups. To evaluate the adherence to different doses of CCT intervention. Participants will: Receive CCT intervention at varying durations and frequencies over a 12-week period, and will be followed up for cognitive function, functional activity ability, etc., at weeks 4, 12, and 24.

Conditions

• Mild Cognitive Disorder

Interventions

Type	Name	Description
DEVICE	Computerized Cognitive Training	Computerized Cognitive Training (30 minutes per session, 3 sessions per week, for a 12-week period)
DEVICE	Computerized Cognitive Training	Computerized Cognitive Training (45 minutes per session, 3 sessions per week, for a 12-week period)
DEVICE	Computerized Cognitive Training	Computerized Cognitive Training (60 minutes per session, 3 sessions per week, for a 12-week period)
DEVICE	Computerized Cognitive Training	Computerized Cognitive Training (30 minutes per session, 5 sessions per week, for a 12-week period)
DEVICE	Computerized Cognitive Training	Computerized Cognitive Training (45 minutes per session, 5 sessions per week, for a 12-week period)
DEVICE	Computerized Cognitive Training	Computerized Cognitive Training (60 minutes per session, 5 sessions per week, for a 12-week period)

Timeline

• Start date: 2025-10-08
• Primary completion: 2026-06-01
• Completion: 2026-12-01
• First posted: 2025-10-08
• Last updated: 2025-10-08