Trials / Completed
CompletedNCT07212946
Ayahuasca and Esketamine for Major Depression
Four Doses of Ayahuasca or Esketamine in Major Depressive Disorder: a Double-blind Randomized Trial
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 22 (actual)
- Sponsor
- University of Sao Paulo · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Double-blind, randomized trial comparing 4 weekly doses of oral ayahuasca and esketamine in patients with major depression.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ayahuasca | Oral |
| DRUG | Esketamine | oral |
Timeline
- Start date
- 2022-10-30
- Primary completion
- 2024-10-30
- Completion
- 2025-10-01
- First posted
- 2025-10-08
- Last updated
- 2025-12-29
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT07212946. Inclusion in this directory is not an endorsement.