Clinical Trials Directory

Trials / Completed

CompletedNCT07211451

Axillary Nodal Burden in HER2+ and TNBC

Low Axillary Nodal Metastasis Rates in Selected HER2-Positive and Triple-Negative Breast Cancer Patients: Toward De-escalation of Sentinel Lymph Node Biopsy

Status
Completed
Phase
Study type
Observational
Enrollment
1,571 (actual)
Sponsor
Gangnam Severance Hospital · Academic / Other
Sex
Female
Age
19 Years
Healthy volunteers
Not accepted

Summary

This study aimed to evaluated rates of pathologic axillary nodal metastasis in patients with with early-stage HER2-positive BC or TNBC who had clinically node-negative status on preoperative ultrasonography and underwent upfront breast-conserving surgery (BCS) with axillary surgery. In addition, this study aimed to identify subgroups in which SLNB omission may be feasible.

Conditions

Interventions

TypeNameDescription
PROCEDUREBreast conserving surgery with axillary surgeryIn this study, all patients received breast conserving surgery with axillary surgery.

Timeline

Start date
2025-06-01
Primary completion
2025-08-31
Completion
2025-09-30
First posted
2025-10-08
Last updated
2025-10-08

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT07211451. Inclusion in this directory is not an endorsement.