NCT07211308

Open and Closed Loop DTM SCS in Patients With PSPS Type 2: ENDLESS Study

Open and Closed Loop Differential Target Multiplexed Spinal Cord Stimulation in Patients With Persistent Spinal Pain Syndrome Type II: a European Multicenter Cohort Study (ENDLESS)

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Universitair Ziekenhuis Brussel · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Evaluation of the effectiveness of differential target multiplexed spinal cord stimulation for treatment of Persistent Spinal Pain Syndrome Type II (PSPS-T2). Identification of clinical effective parameters concerning frequency, pulse duration, amplitude and battery consumption/recharge frequency and safety evaluation.

Conditions

• Persistent Spinal Pain Syndrome Type 2
• Failed Back Surgery Syndrome
• Failed Neck Surgery Syndrome

Interventions

Type	Name	Description
DEVICE	Spinal Cord Stimulation	Differential target multiplexed stimulation

Timeline

• Start date: 2025-10-01
• Primary completion: 2028-01-01
• Completion: 2029-01-01
• First posted: 2025-10-07
• Last updated: 2025-10-07

Locations

2 sites across 1 country: Belgium