NCT07210918

Serum Trace Element Levels in Some Gynecological Diseases

Serum Trace Element Profiles in Women With Endometriosis, Ovarian and Endometrial Cancer: An ICP-MS-Based Comparative Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Cumhuriyet University · Academic / Other
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The aim of this clinical study is to measure the levels of various trace elements in the blood serum of women with various gynecological diseases and to compare them with healthy controls. The main questions it aims to answer are: * Do trace element levels increase or decrease in endometriosis? * Do trace element levels increase or decrease in ovarian cancer patients? * Do trace element levels increase or decrease in endometrial cancer patients? Participants: Each member of the study group will visit the clinic only once and donate 5 ml of blood.

Detailed description

However, the serum trace elements profiles of individuals with endometriosis, ovarian cancer (OC), and endometrial cancer (EC) are not fully known. The purpose of this study is to examine the levels of trace element profiles in the blood serum of healthy people and individuals with gynecological disorders. The study group comprised of 40 women divided into four groups (n=10 each); endometriosis, endometrial cancer and ovarian cancer, and control group who were obstetrically and demographically similar. Inductively coupled plasma-mass spectrometry (ICP-MS) was used to assess serum trace element levels of lead, beryllium, vanadium, chromium, manganese, iron, cobalt, nickel, arsenic, selenium, molybdenum, cadmium, antimony, and phosphorus

Conditions

• Endometriosis
• Endometrial Cancer
• Over Cancer
• Healthy Control

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Blood Product	5 mL of blood was collected from the right arms of all individuals in 4 different groups. Their serum was obtained.

Timeline

• Start date: 2025-04-24
• Primary completion: 2025-09-29
• Completion: 2025-09-29
• First posted: 2025-10-07
• Last updated: 2025-11-24

Locations

1 site across 1 country: Turkey (Türkiye)