NCT07207382

Clinical and Radiographic Evaluation of Three Biomimetic Materials in Pulp Therapy of Immature Young Permanent Teeth "A Randomized Controlled Clinical Trial"

• Status: Active Not Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 69 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 7 Years – 10 Years
• Healthy volunteers: Accepted

Summary

Statement of the problem: Pulpotomy is the most popular technique for maintaining vitality and has a substantial impact on continuing root growth in vital, young permanent molars suffering from dental cavities. Biomimetic materials placement after performing pulp therapy is one of the important factors to determine healing of the pulp and continue root formation. In this study a novel material "Treated Dentin Matrix" is used in comparison to premixed bioceramic material and "Mineral Trioxide Aggregate" in pulpotomy of immature permanent molars. The Aim of the study: Is to assess the clinical and radiographic success of pulpotomized first permanent immature molars treated with three different Biomimetic materials (Treated Dentin Matrix, Premixed Bio-ceramic material and Mineral Trioxide Aggregate)

Conditions

• Pulpotomy of Young Permanent Molars

Interventions

Type	Name	Description
DRUG	MTA group	MTA group is considered the control group
DRUG	Premixed Bioceramic material	Premixed Bioceramic material is test group B
DRUG	Treated Dentin Matrix	Treated Dentin Matrix is test group C

Timeline

• Start date: 2024-02-20
• Primary completion: 2026-08-01
• Completion: 2026-10-01
• First posted: 2025-10-06
• Last updated: 2026-04-13

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study