NCT07207200

Impact of Morning Light Therapy in IBD

The Effects of Morning Light Therapy on IBD Activity and Symptoms

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Icahn School of Medicine at Mount Sinai · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The pilot study will focus on the effects of morning light therapy (MLT) in adult patients with ulcerative colitis (UC) who have evidence of poor sleep quality and active inflammation. The specific population is at risk for circadian rhythm sleep-wake disorders and has significant potential benefit from circadian realignment, which may lead to improved sleep quality and, ultimately, UC-related inflammatory activity. During an initial one-week lead-in period, participants will obtain baseline circadian-related labs, complete symptom-related surveys, and use a wearable device continuously to obtain baseline sleep-wake data. After the lead-in week, patients will undergo one hour of MLT while wearing wearable devices continuously and completing daily symptom surveys. At the end of four weeks of MLT, patients will obtain post-intervention circadian and inflammatory assessments in addition to completing the same symptom-related surveys.

Conditions

• Inflammatory Bowel Disease

Interventions

Type	Name	Description
DEVICE	Morning Light Therapy	One hour of morning light therapy each day for four weeks

Timeline

• Start date: 2026-03-01
• Primary completion: 2027-07-01
• Completion: 2027-07-01
• First posted: 2025-10-03
• Last updated: 2026-03-13

Locations

1 site across 1 country: United States