NCT07205640

Improving Healing in Children After Tooth Extraction Using Laser Therapy or Hyaluronic Acid

Effect of Low-Level Laser Therapy Versus Hyaluronic Acid on Wound Healing After First Permanent Molar Extraction in Children.

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 6 Years – 10 Years
• Healthy volunteers: Accepted

Summary

Tooth extraction may be an unpleasant and painful experience for children, Post-extraction wound healing. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing, resulting in both an increase in cell number and an increase in cell metabolism. HA it is an important component of the extracellular matrix and a constituent of the neural, connective, and epithelial tissues.

Detailed description

Tooth extraction may be an unpleasant and painful experience for children. Pain felt during dental treatment, especially tooth extraction, is the most common complication. Pain management during and after tooth extraction is part of behavioral guidance, especially in pediatric patients. Post-extraction wound healing and pain perception are related to hostrelated factors such as the patient's immune system, the use of painkillers and antibiotics, the presence of infection in the region, and the atraumatic nature of the procedure. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing. It is based on the idea that exposure to a specific wavelength can alter cellular behavior, resulting in both an increase in cell number and an increase in cell metabolism. Aside from not having any negative effects, LLLT is an a thermic, photobiological, and nondestructive therapy approach. HA it is an important component of the extracellular matrix and a constituent of the neural, connective, and epithelial tissues. Among the many biological effects of HA are its functions in cell differentiation, wound healing, inflammation, embryological development, and viscoelasticity.

Conditions

• Mesh
• Healthy Volunteer
• Low Level Laser Therapy
• Hyaluronic Acid Gel for Preservation the Extraction Socket
• Extraction Socket Healing
• Badly Decayed Molars
• Tooth Extraction Site Healing

Interventions

Type	Name	Description
DEVICE	Low-Level Laser Therapy	A 980 nm diode laser will be applied immediately after extraction of the first permanent molar. The laser will be used in continuous mode at 0.5 W, with a total energy of 300 J, applied for 60 seconds at three points around the extraction socket.
DRUG	Hyaluronic Acid (HA)	Hyaluronic acid gel will be applied directly into the extraction socket immediately after tooth removal.

Timeline

• Start date: 2025-12-01
• Primary completion: 2025-12-01
• Completion: 2026-12-01
• First posted: 2025-10-03
• Last updated: 2025-10-03

Locations

1 site across 1 country: Egypt