NCT07200817

Neutrophils to Lymphocytes and Platelets Ratio, Procalcitonin, and Total Leucocytic Count as Indicators of Prognostic Outcome in Septic Patients in the Intensive Care Unit.

Comparison Between Neutrophils to Lymphocytes and Platelets Ratio, Procalcitonin, and Total Leucocytic Count as Indicators of Prognostic Outcome in Septic Patients in the Intensive Care Unit.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 290 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare Neutrophil to Lymphocyte and Platelet Ratio, Procalcitonin, and Total Leucocyte Count as indicators of prognostic outcome in septic patients in the intensive care unit.

Detailed description

Sepsis affects more than 30 million people annually worldwide and is one of the significant causes of death in critical patients worldwide. Any infected person can potentially develop sepsis, and the incidence of sepsis is as high as 1-2% of all hospitalized patients. Many potential sepsis biomarkers have been proposed, procalcitonin (PCT) and C-reactive protein (CRP) being the most frequently studied. The ratio of neutrophils to lymphocytes and platelets (N/LP) is a low-cost measure that can be obtained through routine blood tests and is often used to reflect the body's inflammatory state.

Conditions

• Neutrophils to Lymphocytes
• Platelets
• Procalcitonin
• Total Leucocytic Count
• Prognostic Outcome
• Septic Patients
• Intensive Care Unit

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Neutrophils to Lymphocytes and Platelets ratio (N/LP)	The Neutrophils to Lymphocytes and Platelets ratio (N/LP) will be measured

Timeline

• Start date: 2024-09-20
• Primary completion: 2026-03-19
• Completion: 2026-03-19
• First posted: 2025-10-01
• Last updated: 2025-10-01

Locations

1 site across 1 country: Egypt