NCT07200531

Does Psychotherapy Change the Gut Microbiome in Women of Child-bearing Age?

Impact of Biopsychosocial Psychotherapy Intervention on Maternal Life-Course Trauma and the Gut Microbiome

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: University of Nebraska · Academic / Other
• Sex: Female
• Age: 19 Years – 54 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if group therapy for six weeks changes the gut microbiome in women. The main questions it aims to answer are: Is chronic stress associated with the gut microbiome? Will six weeks of therapy change the gut microbiota? Participants will: Answer questionnaires about chronic stress Mail a stool sample before and after the intervention. Participate in a 1-hour group therapy session over the course of six weeks.

Conditions

• Chronic Stress

Interventions

Type	Name	Description
BEHAVIORAL	Psychotherapy	6-week psychotherapy group intervention

Timeline

• Start date: 2025-12-01
• Primary completion: 2026-04-01
• Completion: 2026-07-01
• First posted: 2025-10-01
• Last updated: 2026-03-25

Locations

1 site across 1 country: United States