Clinical Trials Directory

Trials / Completed

CompletedNCT07196280

Protective Effect of 5-Alpha Reductase Inhibitors on Atherosclerotic Cardiovascular Disease in Populations With BPH: Evidence From UK Biobank Cohort and Chinese Single Center Database Studies

Status
Completed
Phase
Study type
Observational
Enrollment
10,000 (estimated)
Sponsor
Chinese PLA General Hospital · Academic / Other
Sex
Male
Age
45 Years
Healthy volunteers
Not accepted

Summary

To assess the impact of 5-alpha reductase inhibitors (5-ARIs) on the incidence of atherosclerotic cardiovascular disease (ASCVD) in patients with benign prostatic hyperplasia (BPH).

Conditions

Interventions

TypeNameDescription
DRUG5-Alpha Reductase InhibitorsBuilding on prior studies, drug exposure was defined as receiving 5-ARIs on at least two separate occasions, with an interval of no more than 180 days between prescriptions. Based on exposure status, the cohort was stratified into two groups.

Timeline

Start date
2012-01-01
Primary completion
2022-12-31
Completion
2022-12-31
First posted
2025-09-29
Last updated
2025-09-29

Source: ClinicalTrials.gov record NCT07196280. Inclusion in this directory is not an endorsement.