NCT07195097

Sildosin as a Male Contraceptive Non Hormonal

A Prospective Study to Evaluate the Efficacy of Silodosin 8 mg as an on-Demand, Reversible, Nonhormonal Oral Contraceptive for Males:

• Status: Not Yet Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Benha University · Academic / Other
• Sex: Male
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

In all, 200 healthy, sexually active, fertile male candidates will be assigned 100 in silodosin group and 100 in placebo group. Males using other contraceptive methods will be excluded. Follow up data of total spermatozoa per ejaculate, semen volume and Post-ejaculation urinalysis after 2, 6 and 12 weeks of the studied groups will be recorded. The various side effects reported in the study groups after 12 weeks from the start of the study will be recorded.

Conditions

• Contraception Use

Interventions

Type	Name	Description
DRUG	Oral intake of sildosin	Oral intake of sildosin in male non hormonal contraception
OTHER	Oral intake of placebo	Intake of placebo to compare effecacy of other group

Timeline

• Start date: 2025-09-01
• Primary completion: 2025-11-01
• Completion: 2025-12-01
• First posted: 2025-09-26
• Last updated: 2025-09-26