NCT07193849

Zinc Oxide VS MEBO

Impact of Using Zinc Oxide Versus Moist Exposed Wound Ointment (MEBO) in Treatment of Second Stage Pressure Ulcer: A Randomized Control Clinical Trial

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 76 (estimated)
• Sponsor: King Abdullah Medical City · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

randomize control trial to evaluate the efficacy of using zinc oxide versus moist exposed wound ointment in treatment of second stage pressure ulcer.

Detailed description

In this study the subject will be randomized using electronic randomization 1:1 ratio. The randomization list was generated electronically through R using the Random Allocation Rule. The data will be collected using Assessment sheet of patient with second stage pressure ulcer tool. Patients will equally be allocated into 2 groups randomly. The zinc oxide group will receive topical zinc oxide twice every 12 hours daily and patients in the MEBO group will receive topical MEBO ointment twice every 12 daily. Patient will be examined daily till complete healing for the pressure ulcer and maximum one month. The Bates-Jensen Wound Assessment Tool (BWAT) will be used to evaluate wound healing. It is a validated wound assessment tool which is used in many healthcare settings for wound assessment

Conditions

• Pressure Injury
• Pressure Injury Stage 2
• Bedsore
• Pressure Ulcers Stage II
• Pressure Ulcer, Buttock

Interventions

Type	Name	Description
DRUG	MEBO Wound Ointment	both are used for second pressure ulcer
DRUG	zinc oxide	both are used to treat second degree pressure ulcer but with no superiority

Timeline

• Start date: 2023-12-31
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2025-09-26
• Last updated: 2025-09-26

Locations

2 sites across 1 country: Saudi Arabia