NCT07193563

A Study to Evaluate the Efficacy and Safety of ENX-102 in Participants With Social Anxiety Disorder

The ENCalmSocial Trial: A Randomized, Double-Blind, Placebo-Controlled Monotherapy Trial to Evaluate the Efficacy and Safety of ENX-102 in Participants With Social Anxiety Disorder

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 47 (actual)
• Sponsor: Engrail Therapeutics INC · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This is a double-blind study to evaluate the efficacy and safety of ENX-102 in participants with social anxiety disorder (SAD).

Conditions

• Social Anxiety Disorder (SAD)

Interventions

Type	Name	Description
DRUG	ENX-102	oral capsule
OTHER	Placebo	oral capsule

Timeline

• Start date: 2025-09-05
• Primary completion: 2026-03-19
• Completion: 2026-03-19
• First posted: 2025-09-26
• Last updated: 2026-04-08

Locations

20 sites across 1 country: United States

Regulatory

• FDA-regulated drug study