Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07192211

Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo CABG

Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo Coronary Artery Bypass Surgery

Status
Not Yet Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
50 (estimated)
Sponsor
Rohto Pharmaceutical Co., Ltd. · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

ADR-002K is administered to heart failure patients with ischemic heart disease who undergo coronary artery bypass surgery (CABG) to investigate its efficacy and safety.

Detailed description

This is a multicenter, randomized, double-blind, placebo-controlled Phase II study. ADR-002K (Adipose-derived mesenchymal stem cells) is administered to the surface of the heart in patients with ischemic heart disease who undergo CABG. The efficacy and safety of ADR-002K are evaluated until the last patient has completed the 2-year evaluation.

Conditions

Interventions

TypeNameDescription
BIOLOGICALMesenchymal stem cellADR-002K administration
BIOLOGICALPlaceboPlacebo

Timeline

Start date
2025-09-01
Primary completion
2028-09-30
Completion
2029-03-31
First posted
2025-09-25
Last updated
2025-09-25

Source: ClinicalTrials.gov record NCT07192211. Inclusion in this directory is not an endorsement.