NCT07191665

Explore the Use of Cortical Oxygenation Measures in Nutrition Research

Exploring Cortical Oxygenation Modulations in Response to Dietary Components During Cognitive Activity in Healthy Adults: a fNIRS Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 37 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 25 Years – 35 Years
• Healthy volunteers: —

Summary

The current project aims to explore the use of cortical oxygenation measures obtained with functional Near Infrared Spectroscopy (fNIRS) in acute nutrition interventions with outcomes on cognition.

Detailed description

The project aims to test a previously developed fNIRS-based protocol for evaluating the acute effects of dietary components on cognitive function in a population of healthy young adults. The testing will involve detecting patterns in fNIRS-based cortical tissue oxygenation level and cognitive performance that are expected due to the bioactive mechanisms of the studied components.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Acute nutrition intervention	The products (investigational and placebo) consists of three capsules that should be taken with water at two separate visits, with a wash-out period in between. The placebo product will comprise of microcrystalline cellulose (bulk). The investigational products will contain either caffeine and microcrystalline cellulose or caffeine, L-Arginine, and microcrystalline cellulose.

Timeline

• Start date: 2023-11-20
• Primary completion: 2024-06-30
• Completion: 2025-08-31
• First posted: 2025-09-25
• Last updated: 2025-09-25

Locations

1 site across 1 country: Switzerland