NCT07190924

Inflammatory Responses After CrossFit and Resistance Trainings in Untrained Subjects

The Effect of a CrossFit Training Program on Physical, Physiological, and Hormonal Responses in Untrained Subjects

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Habil Hamdouni · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Considering the remarkable increase of the fitness programs, the purpose of this study was to assess and compare the effect of Crossfit (CF) and periodized resistance (RT) trainings on inflammatory/oxidative responses in untrained individuals. Twenty-four participants (20 men and 4 women, age= 25.7 ± 2.2 years, BMI= 25.7 kg.m-2) were randomly assigned into 12 weeks of these trainings with a rate of five sessions/week. Before and after intervention, participants anthropometric data and graded exercise tests were performed. Before (pre), immediately after (post) and 60min after test (p60) a 20mL venous blood sample were drawn for a later measure of c-reactive protein (CRP), interleukin 1 beta (IL-1ß), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), interleukin 10 (IL-10), thiobarbituric acid reactive substances (TBARS), antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx).

Conditions

• Inflammation
• Oxidative Stress
• Plasma Volume
• Hormones

Interventions

Type	Name	Description
BEHAVIORAL	12 week training	Anti-inflammatory and oxidative environment following 12-weeks of CF training by evaluating inflammatory markers and oxidative precursors in untrained participants
BEHAVIORAL	12 week training	Anti-inflammatory and oxidative environment following 12-weeks of resistance training by evaluating inflammatory markers and oxidative precursors in untrained participants

Timeline

• Start date: 2021-11-08
• Primary completion: 2022-02-08
• Completion: 2022-04-17
• First posted: 2025-09-24
• Last updated: 2025-09-24

Locations

1 site across 1 country: Tunisia