NCT07187414

Microbiological Description of Sperm and Follicular Fluid Samples. Impact on IVF/ICSI Success Rates

Microbiological Description of Sperm and Follicular Fluid Samples. Impact on IVF/ICSI Success Rates (SPERMIBIOTE)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche · Academic / Other
• Sex: All
• Age: 18 Years – 59 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to quantify and identify bacteria that may be present in semen and follicular fluid samples on the day of the IVF-ICSI attempt. The secondary objective is to : * Quantify and identify bacteria that may be present in embryo culture media on day 6. * Correlate microbiological analyses of sperm and follicular fluids with those of embryo culture media on day 6. * Evaluate their impact on fertilization and blastulation rates

Detailed description

This is a single-center observational study based on data contained in the medical records of couples treated and evaluated as part of Medically Assisted Procreation (IVF-ICSI). This study was conducted at the Parly 2 private hospital for data and sample collection, at the Parly 2 hospital microbiology laboratory, and at Life \& Soft Fontenay-aux-Roses for sample analysis. Collected samples will not be stored after analysis. The objective of this study does not impose any particular constraints. The study consists of a single assessment, the data from which will be recorded on an electronic case report form (CRF).

Conditions

• In Vitro Fertilization (IVF)
• Medically Assisted Procreation (MAP)

Timeline

• Start date: 2024-01-09
• Primary completion: 2025-03-29
• Completion: 2025-03-29
• First posted: 2025-09-23
• Last updated: 2025-09-23

Locations

1 site across 1 country: France