NCT07186556

Cancer-related Fatigue and Its Biological Contributors in Adolescent and Young Adult Brain Tumor Survivors: Effects of a Tele-exercise Intervention

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years – 39 Years
• Healthy volunteers: Not accepted

Summary

The goal of this research study is to learn about the effects of the RISE-YA intervention on cancer-related fatigue in young adults who are brain cancer survivors.

Detailed description

Primary Objective: Test the efficacy of RISE-YA to improve CRF Secondary Objectives: 1. Test the efficacy of RISE-YA to improve PA and physical function in fatigued YA brain tumor survivors. 2. Determine A) cross-sectional associations of CRF with oxidative phosphorylation (OxPhos) and with inflammation, and B) the effect of RISE-YA on OxPhos and on inflammation. Exploratory Objective: Assess the effect of our supervised exercise intervention on patient-reported health-related quality of life, muscle mass development (BMI, skinfold and circumferences \[waist, arm, and calf area\]), patient-reported dietary intake, and exercise adherence and progression.

Conditions

• Cancer
• Fatigue
• Brain Tumor Adult

Interventions

Type	Name	Description
BEHAVIORAL	RISE-YA Intervention	Participants will receive energy conservation (EC) counseling, behavior coaching, and exercise training.
BEHAVIORAL	Survivorship Education	During weeks 1-6 and 1 time a week during Weeks 7-12, participants will receive a video call which will last about 60 minutes.

Timeline

• Start date: 2025-09-09
• Primary completion: 2029-12-31
• Completion: 2031-12-31
• First posted: 2025-09-22
• Last updated: 2026-03-04

Locations

1 site across 1 country: United States